姓名:胡江苗
学科:药用植物化学
电话:+86-871-65223264
传真:+86-871-65223261
电子邮件:hujiangmiao@mail.kib.ac.cn
通讯地址:云南省昆明市蓝黑路132号,邮编:650201
简历:
1998.9 – 2002.7, 安徽中医药大学药学院中药学专业学习,学士。
2002.9 – 2007.6, 中科院昆明植物所植化重点室植物化学专业学习,师从周俊研究员,硕士,博士。
2007.7 – 2009.12, 中科院昆明植物所植化重点室助理研究员。
2010.1 – 今, 中科院昆明植物所植化重点室副研究员。
2013年,遴选为中科院昆明植物所药物化学方向硕士研究生导师。
2015年,云南省中青年学术技术带头人后备人才。
研究领域:药用植物资源化学。
开展石斛、天麻等兰科部分药用植物的化学药理学研究;开展高活性天然产物结构修饰与活性跟踪研究。
近三年代表性论文 (通讯作者):
1. Zhen-Hua Liu,Bo Hou, Liu Yang, Rui-Jing Ma, Jin-Yu Li, Jiang-Miao Hu and Jun Zhou. Iridoids and bis-iridoids from Patrinia scabiosaefolia. RSC advance, 2017, 7: 24940-24949.
2. Zhen-Hua Liu, Rui-Jing Ma, Liu Yang, Jin-Yu Li, Bo Hou, Jiang-Miao Hu, Jun Zhou. Triterpenoids and iridoids from Patrinia scabiosaefolia. Fitoterapia, 2017, 119: 130–135
3. Feng-Qing Xu, NingWang, Wei-Wei Fan, Cheng-Ting Zi, Hong-Su Zhao, Jiang-Miao Hu, Jun Zhou. Protective effects of cycloartane triterpenoides from Passiflora edulis Sims against glutamate-induced neurotoxicity in PC12 cell, Fitoterapia, 2016, 115, 122–127
4. Rui-Jing Ma, Zhen-Hua Liu, Cheng-Ting Zi, Wei Gao, Fa-Wu Dong, Liu Yang, Jin-Yu Li, Jun Zhou, Jiang-Miao Hu. Oleanane-type triterpene saponins from Hydrocotyle nepalensis, Fitoterapia, 2016, 110, 66-71.
5. Tao-Bin He, Yan-Ping Huang, Liu yang, Ti-Ti Liu, Wan-Ying Gong, Xuan-Jun Wang, Jun Sheng, Jiang-Miao Hu. Structural characterization and immunomodulating activity of polysaccharide from Dendrobium officinale, International Journal of Biological Macromolecules, 2016, 83, 34-41
6. Fa-Wu Dong, Zhi-Kun Wu, Liu Yang, Chen-Ting Zi, Dan Yang, Rui-Jing Ma, Zhen-Hua Liu, Huai-Rong Luo, Jun Zhou, Jiang-Miao Hu. Iridoids and sesquiterpenoids of Valeriana stenoptera and their effects on NGF-induced neurite outgrowth in PC12 cells, Phytochemistry, 2015, 118, 51-60.
7. Cheng-Ting Zi, Gen-Tao Li, Yan Li, Jun Zhou, Zhong-Tao Ding, Zi-Hua Jiang, Jiang-Miao Hu. Synthesis and anticancer activity of 4β-triazole-podophyllotoxin glycosides, Natural Products and Bioprospecting, 2015, 5: 83–90
8. Cheng-Ting Zi, Dan Yang, Fa-Wu Dong, Gen-Tao Li, Yan Li, Zhong-Tao Ding, Jun Zhou, Zi-Hua Jiang and Jiang-Miao Hu. Synthesis and antitumor activity of novel per-butyrylated glycosides of podophyllotoxin and its derivatives, Bioorganic & Medicinal Chemistry, 2015, 23: 1437-1446
9. Cheng-Ting Zi, Zhen-hua Liu, Gen-Tao Li, Yan Li, Jun Zhou, Zhong-Tao Ding, Jiang-Miao Hu, Zi-Hua Jiang. Design, synthesis, and cytotoxicity of per-butyrylated glycosides of 4β-triazole-podophyllotoxin derivatives. Molecules, 2015, 20(2):3255-3280
10. Fa-Wu Dong; Liu Yang; Zhi-Kun Wu; Wei Gao; Cheng-Ting Zi; Dan Yang; Huai-Rong Luo; Jun Zhou; Jiang-Miao Hu. Iridoids and sesquiterpenoids from the roots of Valeriana jatamansi Jones. Fitoterapia, 2015, 102, 27-34.
11. Dan Yang, Liang-Yan Liu, Zhong-Quan Cheng, Feng-Qing Xu, Wei-Wei Fan, Cheng-Ting Zi, Fa-Wu Dong, Jun Zhou, Zhong-Tao Ding , Jiang-Miao Hu. Five new phenolic compounds from Dendrobium aphyllum. Fitoterapia, 2015, 100, 11-18.
12. Liu Yang, Shoujin Liu, Huai-Rong Luo, Juan Cui, Jun Zhou, Xuanjun Wang, Jun Sheng, Jiangmiao Hu. Two New dendrocandins and neurite outgrowth-promoting activity from Dendrobium officinale. Journal of Asian Natural Products Research, 2015, 17 (2), 125-131.
主持项目:
生物素及糖苷化修饰鬼臼毒素类似物抗肿瘤药物研发,云南省面上项目/2015FB168,项目经费:10万元。
云南省科技厅社会发展科技计划子课题,云南铁皮石斛质量标准体系制订 (2012.3-2014.6),项目经费:65 万元。
国家自然科学基金面上项目青年人才基金,几种石斛属植物与药典石斛的药学对比研究 (No: 1130800090, 2009.1-2011.12),批准金额:19万元。
中科院西部之光西部博士项目,四种石斛属植物与药典石斛的药学对比研究 (No: 292009312D11017, 2010.1-2013.6), 批准金额:10万元。
Name: Hu Jiangmiao
Subject:Phytochemistry or Chemistry of Traditional Chinese Medicine
Tel.: +86-871-5223264
Fax: +86-871-5223261
E-mail:hujiangmiao@mail.kib.ac.cn
Add.: 132#, Lanhei Road, Kunming 650204, Yunnan, China
Experience:
1998.9 – 2002.7 Bachelor's degree majored in Traditional Chinese Medicine in Anhui College of Traditional Chinese Medicine.
2002.9 – 2007.6 Doctor degree majored in phytochemistry after Prof. Zhou Jun in Kunming Institute of Botany, Chinese Academy of Science.
2007.7 – 2009.12 Assistant Professor, Kunming Institute of Botany, Chinese Academy of Sciences.
2010.1 – Present Associate Professor, Kunming Institute of Botany, Chinese Academy of Sciences.
Research Areas:Natural products and medicinal chemistry.
Representative Articles:
1. Fengqing Xu, Cong Wang, Liping Yang, Huairong Luo, Weiwei Fan, Chengting Zi, Fawu Dong, Jiangmiao Hu, Jun Zhou. C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims, Food Chemistry 2013, 136, 94-99.
2. Wei-Wei Fan, Feng-Qing Xu, Fa-Wu Dong, Xiao-Nian Li, Xiao-Yong Wei, Jun Zhou, Jiang-Miao Hu. Dendrowardols A and B, Two New Sesquiterpenoids from Dendrobium wardianum Warner. Tetrahedron Letters, 2013, 54, 1928-1930
3. Cong Wang, Feng-Qing Xu, Jian-Hua Shang, HuaiXiao, Wei-Wei Fan, Fa-Wu Dong Jiang-Miao Hu, Jun Zhou. Cycloartane triterpenoids aponins from water soluble of Passiflora edulis Sims. and their antidepressant-like effects. Journal of Ethnopharmacology, 2013, 148, 812-817.
4. Peng-Cheng Wang, Xin-Hui Ran, Huai-Rong Luo, Yi-Min Zheng, Yu-Qing Liu, Jiang-Miao Hu, Jun Zhou. Nardokanshone A, a new type of sesquieterpenoid–chalcone hybrid from Nardostachys chinensis. Tetrahedron Letters, 2013, 54, 4365-4368.
5. Cheng-Ting Zi, Feng-Qing Xu, Gen-Tao Li, Yan Li, Zhong-Tao Ding, Jun Zhou, Zi-Hua Jiang and Jiang-Miao Hu. Synthesis and Anticancer Activity of Glucosylated Podophyllotoxin Derivatives Linked via 4β-Triazole Rings. Molecules, 2013, 18, 13992-14012.
6. Cheng-Bo Li, Cong Wang, Wei-Wei Fan, Fa-Wu Dong, Feng-Qing Xu, Qin-Li Wan, Huai-Rong Luo, Yu-Qing Liu, Jiang-Miao Hu, and Jun Zhou. Chemical components of Dendrobium crepidatum and their neurite outgrowth enhancing activities. Natural Products and Bioprospecting, 2013, 3, 70-73.
7. Wei-Wei FAN, Feng-Qing XU, Fa-Wu DONG, Xiao-Nian LI, Yan LI, Yu-Qing LIU, Jun ZHOU, and Jiang-Miao HU, Dendrowardol C, a novel sesquiterpenoid from Dendrobium wardianum Warner. Natural Products and Bioprospecting, 2013, 3, 89-92.
8. Jiang-Miao Hu, Weiwei Fan, Fa-Wu Dong, Ze-Hong Miao and Jun Zhou. Chemical components of Dendrobium chrysotoxum, Chinese Journal of Chemistry 2012, 30, 1327-1330.
9. Dong, F.-W.; Luo, H.-R.; Wan, Q.-L.; Xu, F.-Q.; Fan, W.-W.; Wang, K.-J.; Li, N.; Hu, J.-M., Two new bibenzyl glucosides from Dendrobium chrysotoxum, Bullitin of the Korean Chemical Society 2012, 33, 2247-2250.
10. Hu, J.-M.; Fan, W.-W.; Zhou, L.; Zhao, Y.-X.; Zhou, J., A New Phenolic Compound from Dendrobium longicornu. Bulletin of the Korean Chemical Society 2010, 31 (10), 3025-3026.
11. Hu, J.-M.; Zhao, Y.-X.; Chen, J.-J.; Miao, Z.-H.; Zhou, J., A new spongilipid from the freshwater sponge Spongilla lacustris. Bulletin of the Korean Chemical Society 2009, 30 (5), 1170-1172.
12. Hu, J.-M.; Zhao, Y.-X.; Miao, Z.-H.; Zhou, J., Chemical components of Dendrobium polyanthum. Bulletin of the Korean Chemical Society 2009, 30 (9), 2098-2100.
13. Hu, J.-M.; Chen, J.-J.; Yu, H.; Zhao, Y.-X.; Zhou, J., Two novel bibenzyls from Dendrobium trigonopus. Journal of Asian Natural Products Research 2008, 10 (7), 647-651.
14. Hu, J.-M.; Chen, J.-J.; Yu, H.; Zhao, Y.-X.; Zhou, J., Five new compounds from Dendrobium longicornu. Planta Medica 2008, 74 (5), 535-539.