导师简介——程志非
发布人:  发布时间:2021-09-14   浏览次数:

程志非,男,1991年6月出生,校聘研究员,安徽中医药大学药剂学硕士研究生导师。2020年毕业于南开大学,获理学博士学位。主要研究方向:中药新剂型研发;生物医用功能材料制备。迄今在国际著名期刊发表SCI论文12篇,其中中科院1区TOP文章8篇(影响因子高于10的3篇),获得国家发明专利2项,主持/参与科研项目3项。本课题组招收药剂学和药学专业硕士,欢迎研究生和本科生加入课题组共同学习与进步!

1、近年来主持和参与科研项目情况

(1)安徽省教育厅高校与合肥综合性国家科学中心协同创新项目子项目,项目名称:肽基纳米药物及其抗肿瘤光治疗研究,15万,在研,主持

(2)安徽省教育厅高等学校自然科学研究重点项目,项目名称:基于肿瘤微环境响应形态调控的多肽纳米诊疗试剂用于乳腺癌成像与治疗研究,6万,资助期满,主持

(3)安徽中医药大学人才支持计划项目,项目名称:肿瘤微环境响应的可控形态多肽自组装研究,20万,在研,主持

2、近5年来发表有代表性学术论文与专利:

代表性学术论文

(1)Yumeng Xing, Jianhui Yang, Chun Wang, Ziyao Kang, Zheng Pan, Jihui Tang, Fenghe Li, Xiao Wang, Xiaoming Meng, Zhifei Cheng*, Yang Liu*, Qi Liu*. Time-programmed activation of CD47 disruption and immunogenic cell death with Cas9 ribonucleoprotein nanocapsule for improved cancer immunotherapy. Chem. Eng. J., 2023, 474, 145796.(一区TOP,IF=15.1)

(2)Yuxuan Qi, Zhiquan Cai, Chenglong Zheng, Zhifei Cheng*, Shilu Fan*, Yi-Si Feng*. Bimetallic synergy significantly enhances the photocatalytic performance of lanthanide porphyrin-based MOFs: Efficient photocatalytic oxidation of benzyl alcohol and benzylamine under mild conditions in air. J. Catal., 2024, 429, 115226.(一区TOP,IF=7.3)

(3)Zhifei Cheng, Yuanyuan Cheng, Qian Chen, Mingming Li, Jie Wang, Hui Liu, Mengwen Li, Yashan Ning, Zhilin Yu*, Yinsong Wang*, Hao Wang*. Self-assembly of pentapeptides into morphology-adaptable nanomedicines for enhanced combinatorial chemo-photodynamic therapy. Nano Today 2020, 33, 100878.(一区TOP,IF=17.4)

(4)Zhifei Cheng, Shanshan Nai, Shuxin Song, Lingyi Chen* and Zhilin Yu*. Photoinduced directional domain sliding motion in peptide hydrogels promotes ectodermal differentiation of embryonic stem cells. Sci. China Mater. 2020, 63, 467-478.(二区,IF=8.1)

(5)Yumeng Xing, Ao Peng, Jianhui Yang, Zhifei Cheng, Yi Yue, Feilong Liu, Fenghe Li, Yang Liu*, and Qi Liu*. Precisely activating cGAS-STING pathway with a novel peptide-based nanoagonist to potentiate immune checkpoint blockade cancer immunotherapy. Adv. Sci., 2024, 2309583.(一区TOP,IF=15.1)

(6)Fei Tang, Yi-Si Feng*, Zhi-Fei Cheng, Qi Zhang*, and Hua-Jian Xu*. Intermolecular 1,2-difunctionalization of terminal alkynes to access trisubstituted alkenes via copper/photoredox dual catalysis. Org. Lett., 2023, 25, 3916.(一区TOP,IF=5.2)

(7)Yuxuan Qi, Chenglong Zheng, Zhiquan Cai, Zhifei Cheng, Tinghao Yu, Xiao-Xuan Li, Shilu Fan*, and Yi-Si Feng*. 3D lanthanide neodymium porphyrin metal−organic framework for photocatalytic oxidation of styrene. Inorg. Chem., 2023, 62, 8315.(一区TOP,IF=4.6)

(8)Shuxin Song, Jingyu Wang*, Zhifei Cheng, Zhimou Yang, Linqi Shi and Zhilin Yu*. Directional molecular sliding movement in peptide hydrogels accelerates cell proliferation. Chem. Sci., 2020, 11, 1383.(一区TOP,IF=8.4)

国家发明专利

(1)一种植物外泌体-脂质体复合靶向纳米粒载药系统及其制备方法和应用,申请号:CN202311143137.8

(2)一种可变形态的喜树碱多肽纳米制剂及其制备方法和应用,申请号:CN202210596968.X

3、联系方式:

电子邮箱:zfcheng@ahtcm.edu.cn;qq:327020433;办公地址:药学院557